产品货号：
Z24646
中文名称：
PSMC4抗体
英文名称：
Anti-PSMC4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PSMC4 Antibody |
| 指标别名 | PSMC4;MIP224;TBP7;26S proteasome regulatory subunit 6B;26S proteasome AAA-ATPase subunit RPT3;MB67-interacting protein;MIP224;Proteasome 26S subunit ATPase 4;Tat-binding protein 7;TBP-7 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM(Intracellular),Direct ELISA |
| 基因名称 | PSMC4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human PSMC4 recombinant protein (Position:M1-Q412). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | 26S protease regulatory subunit 6B,also known as 26S proteasome AAA-ATPase subunit Rpt3,is an enzyme that in humans is encoded by the PSMC4 gene.The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes,a 20S core and a 19S regulator.The 20S core is composed of 4 rings of 28 non-identical subunits;2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits.The 19S regulator is composed of a base,which contains 6 ATPase subunits and 2 non-ATPase subunits,and a lid,which contains up to 10 non-ATPase subunits.Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly.The encoded protein interacts with gankyrin,a liver oncoprotein,and may also play a role in Parkinson's disease through interactions with synphilin-1.Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Uniprot ID | P43686 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | proteasome 26S subunit,ATPase 4 |
| 蛋白名全称 | 26S proteasome regulatory subunit 6B |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow Cytometry(Intracellular) 1～3μg/1×106 cells Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 5704 |
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